Leronlimab Treatment for Multidrug-Resistant HIV-1 (OPTIMIZE): a Randomized, Double-Blind, Placebo-Controlled Trial Feb 20, 2025
FcRn-enhancing mutations lead to increased and prolonged levels of the HIV CCR5-blocking monoclonal antibody leronlimab in the fetuses and newborns of pregnant rhesus macaques Sep 26, 2024 HIV
Understanding immune dysregulation in post- acute sequelae of COVID-19 (PASC)—The hunt for effective treatments May 9, 2024
Infectious Diseases Society of America: Reduced Cell Surface Levels of C-C Chemokine Receptor 5 and Immunosuppression in Long Coronavirus Disease 2019 Syndrome Apr 22, 2022 COVID-19
PLOS Pathogens: Suppression of human and simian immunodeficiency virus replication with the CCR5-specific antibody Leronlimab in two species Mar 31, 2022 HIV
Leronlimab (PRO 140) in vitro activity against 4-class drug resistant HIV-1 from heavily treatment experienced subjects Feb 28, 2022 HIV
Frontiers in Immunology: CCR5 Receptor Occupancy Analysis Reveals Increased Peripheral Blood CCR5+CD4+ T Cells Following Treatment With the Anti-CCR5 Antibody Leronlimab Nov 19, 2021 HIV
Nature Communications: Antibody-based CCR5 blockade protects Macaques from mucosal SHIV transmission Jun 7, 2021 HIV
Journal of Translational Autoimmunity: Case study of a critically ill person with COVID-19 on ECMO successfully treated with leronlimab Mar 16, 2021 COVID-19
